Mutation MAF summary plot
Introduction
Mutation Annotation Format (MAF) is a TCGA defined file format, used to store mutation annotation informations.
MAF is a specific file format for human species, it contains SNV and annotation informations for all samples, easily for downstream analysis. You can change VCF file into MAF file with vcf2maf. Here we used Masked Somatic Mutation, open access mutation annotation files. ref: maftool R package.
Input data
build-in TCGA 33 types of cancers (TCGA.*.mutect*somatic.maf.gz)
Paper example
M 5 C regulator-mediated methylation modification patterns and tumor microenvironment infiltration characterization in lung adenocarcinoma. Fig2A
Input |
select cancer types and input genes
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Output |
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1) How to plot?
1, Put data in excel according to the example format.
2, Copy and paste into input frame.
3, Input pre-checking button to check input
4, After checking pass, select parameters, submit and download
2) How to cite?
4000+ papers in (Google Scholar)
Tang D, Chen M, Huang X, Zhang G, Zeng L, Zhang G, Wu S, Wang Y. SRplot: A free online platform for data visualization and graphing. PLoS One. 2023 Nov 9;18(11):e0294236. doi: 10.1371/journal.pone.0294236. PMID: 37943830.
3) FAQs